Alnylam Pharmaceuticals, Inc. (ALNY) Shareholders & Insider Trades

Executive TeamFinancialsSegmentsShareholders

Alnylam Pharmaceuticals shareholders at a glance

The largest holder of Alnylam Pharmaceuticals stock is Fidelity Management & Research Co. LLC, with 15.0 million shares (11.23% of the company), worth about $3.62 billion as of September 25, 2026. The 10 largest holders together own 54.5%.

In Q2 2026, 839 institutional holdings reports listed shares worth $42.60 billion.

Insiders reported 99 transactions in the last two years: 43 sales worth $111.89 million and no purchases. The newest one on file is from May 13, 2026 (Schulman Amy W., Director).

Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 13, 2026.

ALNY logo

Alnylam Pharmaceuticals, Inc.

ALNYUnited States
Healthcare

Shareholders Summary

2026Q2

Filings
839
Options Value
$634.00M
Value (excl. Options)
$42.60B
Shares (excl. Options)
-

Ownership by Type

Geographic Distribution

Largest Alnylam Pharmaceuticals shareholders

HolderShares% of companyValue
Fidelity Management & Research Co. LLC15.0 million11.23%$3.6B
Capital Research & Management Co. (World Investors)11.1 million8.33%$2.7B
Capital Research & Management Co. (Global Investors)9.8 million7.29%$2.3B
BlackRock Advisors LLC8.8 million6.55%$2.1B
Vanguard Portfolio Management LLC6.5 million4.89%$1.6B
Vanguard Capital Management LLC6.0 million4.51%$1.5B
T. Rowe Price Investment Management, Inc.5.6 million4.22%$1.4B
Invesco Advisers, Inc.3.8 million2.81%$904.0M
State Street Corporation3.6 million2.66%$856.0M
JPMorgan Investment Management, Inc.2.7 million2.00%$644.0M

As of September 25, 2026.

Alnylam Pharmaceuticals institutional holdings by quarter

QuarterReportsSharesValue
Q2 2026839–$42.6B
Q1 2026833131.0 million$43.4B
Q4 2025908134.0 million$53.2B
Q3 2025879138.0 million$61.3B
Q2 2025704134.0 million$43.3B
Q1 2025690131.0 million$34.9B
Q4 2024645129.0 million$30.1B
Q3 2024623128.0 million$34.7B

Shares and value held by institutions that file quarterly holdings reports (options not included).

Alnylam Pharmaceuticals insider trades

InsiderDateTitleTransactionValue
Schulman Amy W.May 13, 2026DirectorConversion of Exercise of derivative security at price 70.20 per share.$789,750
Mclaughlin MelissaApr 6, 2026OfficerSale at price 316.61 - 333.94 per share.$1.3M
Garg PushkalMar 5, 2026OfficerSale at price 319.03 - 326.08 per share.$1.5M
Fitzgerald Kevin JosephMar 5, 2026OfficerSale at price 319.03 - 326.24 per share.$417,685
Tanguler TolgaMar 4, 2026OfficerSale at price 319.03 - 325.67 per share.$745,984
Poulton Jeffrey VMar 4, 2026Chief Financial OfficerSale at price 319.03 - 325.67 per share.$797,351
Greenstreet Yvonne LMar 4, 2026Chief Executive OfficerSale at price 319.03 - 325.67 per share.$947,581
Garg PushkalMar 3, 2026OfficerSale at price 316.74 - 332.64 per share.$1.1M
Fitzgerald Kevin JosephMar 3, 2026OfficerSale at price 316.55 - 332.64 per share.$1.1M
Greenstreet Yvonne LMar 2, 2026Chief Executive OfficerStock Award(Grant) at price 0.00 per share.–
Supran BryanMar 2, 2026OfficerStock Award(Grant) at price 0.00 per share.–
Fitzgerald Kevin JosephMar 2, 2026OfficerStock Award(Grant) at price 0.00 per share.–

Newest 12 of 99 insider transactions in the last two years.

Questions and answers

Who owns the most Alnylam Pharmaceuticals stock?

Fidelity Management & Research Co. LLC, with 11.23% of the company (as of September 25, 2026). Next: Capital Research & Management Co. (World Investors) (8.33%) and Capital Research & Management Co. (Global Investors) (7.29%).

How many institutions own Alnylam Pharmaceuticals stock?

839 institutional holdings reports listed Alnylam Pharmaceuticals shares in Q2 2026 worth $42.60 billion.

Are Alnylam Pharmaceuticals insiders buying or selling the stock?

In the last two years insiders reported 43 sales and no purchases (99 transactions in all); the newest on file is from May 13, 2026.

Disclaimer: This analysis is for informational and educational purposes only and does not constitute financial, investment, tax, or legal advice. Data may be incomplete, delayed, or contain inaccuracies. Consult with a qualified financial advisor before making any investment decisions.
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