Insmed reported revenue of $606.42 million for fiscal year 2025 (ended December 31, 2025), up 66.7% from fiscal year 2024. Net income was -$1.28 billion, a net margin of 210.5% loss, and diluted earnings per share were -$6.42.
At the end of fiscal year 2025 it had total assets of $2.26 billion, total liabilities of $1.53 billion and shareholders' equity of $738.98 million, with cash and short-term investments of $1.43 billion and total debt of $586.67 million.
Its operations brought in -$935.01 million of cash; capital spending was $32.56 million, leaving free cash flow of -$967.58 million.
The tables below show the income statement, balance sheet and cash flow statement; the key figures of the last 5 fiscal years are at the bottom of the page.
Figures from company filings, in USD; latest fiscal year ended December 31, 2025.

Annual • USD
| FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|
| Revenue | $606.4M | $363.7M | $305.2M | $245.4M | $188.5M |
| Gross profit | $483.5M | $278.0M | $239.6M | $190.2M | $144.3M |
| Operating income | -$994.8M | -$786.6M | -$680.9M | -$478.1M | -$367.8M |
| Net income | -$1.3B | -$913.8M | -$749.6M | -$481.5M | -$434.7M |
| Diluted EPS | -$6.42 | -$5.57 | -$5.34 | -$3.91 | -$3.88 |
| Total assets | $2.3B | $2.0B | $1.3B | $1.7B | $1.2B |
| Total liabilities | $1.5B | $1.7B | $1.7B | $1.6B | $833.0M |
| Shareholders' equity | $739.0M | $285.4M | -$331.9M | $88.0M | $410.5M |
| Cash and short-term investments | $1.4B | $1.4B | $780.4M | $1.1B | $716.8M |
| Total debt | $586.7M | $1.1B | $1.2B | $1.2B | $612.3M |
| Operating cash flow | -$935.0M | -$683.9M | -$536.2M | -$400.4M | -$363.3M |
| Capital spending | $32.6M | $21.9M | $13.3M | $9.9M | $7.3M |
| Free cash flow | -$967.6M | -$705.8M | -$549.5M | -$410.3M | -$370.6M |
In USD. Fiscal years as reported by the company; statements on this page go back to fiscal year 2020.
$606.42 million, up 66.7% from $363.71 million in fiscal year 2024.
Insmed reported net income of -$1.28 billion for fiscal year 2025 (210.5% of revenue); operating income was -$994.78 million.
At the end of fiscal year 2025: cash and short-term investments of $1.43 billion and total debt of $586.67 million.
-$967.58 million in fiscal year 2025 (operating cash flow of -$935.01 million minus capital spending of $32.56 million).