Susan M. Collins won with 49.2% of the vote (298,422 votes), ahead of Joseph E. Brennan with 43.9% (266,226 votes).
The margin between the first two candidates was 5.3 percentage points (32,196 votes). The party margin (Republican share minus Democratic share) was a Republican lead of 5.3 points.
Compared with the previous comparable race in the same area, the party margin moved 18.6 points toward Democrats.
606,777 votes were counted in this race, for 4 candidates or options.
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