Roger F. Wicker won with 55.0% of the vote (683,409 votes), ahead of Ronnie Musgrove with 45.0% (560,064 votes).
The margin between the first two candidates was 9.9 percentage points (123,345 votes). The party margin (Republican share minus Democratic share) was a Republican lead of 55.0 points.
Compared with the previous comparable race in the same area, the party margin moved 26.2 points toward Republicans.
1,243,473 votes were counted in this race, for 2 candidates or options.
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