The largest holder of McKesson stock is BlackRock Advisors LLC, with 8.0 million shares (6.87% of the company), worth about $7.09 billion as of September 25, 2026. The 10 largest holders together own 36.5%.
In Q2 2026, 2,104 institutional holdings reports listed shares worth $80.10 billion.
Insiders reported 96 transactions in the last two years: 41 sales worth $106.69 million and no purchases. The newest one on file is from September 8, 2026 (Rutledge Napoleon B Jr, Officer).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through September 8, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| BlackRock Advisors LLC | 8.0 million | 6.87% | $7.1B |
| Vanguard Capital Management LLC | 7.9 million | 6.74% | $7.0B |
| State Street Corporation | 5.7 million | 4.91% | $5.1B |
| Eaton Vance Management | 5.3 million | 4.55% | $4.7B |
| Vanguard Portfolio Management LLC | 2.9 million | 2.46% | $2.5B |
| Fiduciary Trust Company International | 2.9 million | 2.45% | $2.5B |
| Geode Capital Management LLC | 2.8 million | 2.42% | $2.5B |
| BlackRock Life Ltd. | 2.6 million | 2.23% | $2.3B |
| MFS Investment Management Canada Ltd. | 2.4 million | 2.10% | $2.2B |
| Fidelity Management & Research Co. LLC | 2.1 million | 1.82% | $1.9B |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 2,104 | – | $80.1B |
| Q1 2026 | 2,126 | 107.0 million | $92.4B |
| Q4 2025 | 2,079 | 110.0 million | $89.9B |
| Q3 2025 | 1,926 | 110.0 million | $84.9B |
| Q2 2025 | 1,877 | 112.0 million | $81.9B |
| Q1 2025 | 1,833 | 111.0 million | $74.5B |
| Q4 2024 | 1,757 | 110.0 million | $62.7B |
| Q3 2024 | 1,623 | 115.0 million | $56.4B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Rutledge Napoleon B Jr | Sep 8, 2026 | Officer | Sale at price 891.45 per share. | $98,951 |
| Lerman Bradley E | Aug 10, 2026 | Director | Sale at price 892.32 per share. | $268,590 |
| Caruso Dominic J | Jul 22, 2026 | Director | Stock Award(Grant) at price 814.04 per share. | $225,489 |
| Wilson - Thompson Kathleen | Jul 22, 2026 | Director | Stock Award(Grant) at price 814.04 per share. | $225,489 |
| Martinez Maria N. | Jul 22, 2026 | Director | Stock Award(Grant) at price 814.04 per share. | $225,489 |
| Tyler Brian Scott | Jul 7, 2026 | Chief Executive Officer | Sale at price 793.56 per share. | $6.7M |
| Tyler Brian Scott | Jun 17, 2026 | Chief Executive Officer | Sale at price 775.13 per share. | $6.6M |
| Tyler Brian Scott | Jun 9, 2026 | Chief Executive Officer | Sale at price 763.00 per share. | $3.8M |
| Rutledge Napoleon B Jr | Jun 5, 2026 | Officer | Sale at price 764.00 per share. | $101,612 |
| Rodgers Thomas L | Jun 2, 2026 | Officer | Sale at price 735.27 - 735.50 per share. | $604,420 |
| Smith Leann B | Jun 1, 2026 | Officer | Sale at price 735.50 per share. | $1.3M |
| Rodgers Thomas L | May 26, 2026 | Officer | Sale at price 761.09 per share. | $1.8M |
Newest 12 of 96 insider transactions in the last two years.
BlackRock Advisors LLC, with 6.87% of the company (as of September 25, 2026). Next: Vanguard Capital Management LLC (6.74%) and State Street Corporation (4.91%).
2,104 institutional holdings reports listed McKesson shares in Q2 2026 worth $80.10 billion.
In the last two years insiders reported 41 sales and no purchases (96 transactions in all); the newest on file is from September 8, 2026.