The largest holder of Twist Bioscience stock is BlackRock Advisors LLC, with 5.4 million shares (8.25% of the company), worth about $755.00 million as of September 25, 2026. The 10 largest holders together own 57.4%.
In Q2 2026, 350 institutional holdings reports listed shares worth $7.93 billion.
Insiders reported 100 transactions in the last two years: 80 sales worth $17.62 million and no purchases. The newest one on file is from May 12, 2026 (Johannessen Jan, Director).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 12, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| BlackRock Advisors LLC | 5.4 million | 8.25% | $755.0M |
| Artisan Partners Holdings LP | 4.8 million | 7.29% | $667.0M |
| Fidelity Management & Research Co. LLC | 4.7 million | 7.14% | $654.0M |
| ARK Investment Management LLC | 4.5 million | 6.91% | $632.0M |
| T. Rowe Price International Ltd. | 3.6 million | 5.52% | $505.0M |
| ARK Investment Management LLC | 3.4 million | 5.14% | $471.0M |
| State Street Corporation | 3.2 million | 4.91% | $449.0M |
| Vanguard Portfolio Management LLC | 2.8 million | 4.29% | $393.0M |
| Vanguard Capital Management LLC | 2.7 million | 4.10% | $375.0M |
| Edgepoint Investment Group, Inc. | 2.5 million | 3.83% | $351.0M |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 350 | – | $7.9B |
| Q1 2026 | 291 | – | $3.7B |
| Q4 2025 | 256 | – | $2.4B |
| Q3 2025 | 246 | – | $2.1B |
| Q2 2025 | 254 | 71.3 million | $2.6B |
| Q1 2025 | 272 | 69.8 million | $2.7B |
| Q4 2024 | 259 | 66.4 million | $3.1B |
| Q3 2024 | 254 | 68.6 million | $3.1B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Johannessen Jan | May 12, 2026 | Director | Sale at price 56.12 per share. | $673,440 |
| Johannessen Jan | May 12, 2026 | Director | Conversion of Exercise of derivative security at price 14.00 per share. | $168,000 |
| Werner Robert F. | May 8, 2026 | Officer | Sale at price 56.88 per share. | $282,187 |
| Finn Patrick John | May 4, 2026 | President | Sale at price 57.15 per share. | $162,531 |
| Cho Dennis | May 4, 2026 | Officer | Sale at price 57.15 per share. | $112,126 |
| Leproust Emily M | May 4, 2026 | Chief Executive Officer | Sale at price 57.15 per share. | $293,002 |
| Green Paula | May 4, 2026 | Officer | Sale at price 57.15 per share. | $63,778 |
| Werner Robert F. | May 4, 2026 | Officer | Sale at price 57.15 per share. | $9,372 |
| Starovasnik Melissa A | Apr 27, 2026 | Director | Sale at price 61.83 per share. | $30,915 |
| Finn Patrick John | Apr 23, 2026 | President | Sale at price 60.76 per share. | $141,026 |
| Leproust Emily M | Apr 22, 2026 | Chief Executive Officer | Sale at price 65.01 - 66.00 per share. | $630,957 |
| Leproust Emily M | Apr 22, 2026 | Chief Executive Officer | Conversion of Exercise of derivative security at price 8.82 per share. | $85,298 |
Newest 12 of 100 insider transactions in the last two years.
BlackRock Advisors LLC, with 8.25% of the company (as of September 25, 2026). Next: Artisan Partners Holdings LP (7.29%) and Fidelity Management & Research Co. LLC (7.14%).
350 institutional holdings reports listed Twist Bioscience shares in Q2 2026 worth $7.93 billion.
In the last two years insiders reported 80 sales and no purchases (100 transactions in all); the newest on file is from May 12, 2026.