The largest holder of Guardant Health stock is BlackRock Advisors LLC, with 7.0 million shares (5.24% of the company), worth about $1.12 billion as of September 25, 2026. The 10 largest holders together own 36.5%.
In Q2 2026, 629 institutional holdings reports listed shares worth $20.20 billion.
Insiders reported 100 transactions in the last two years: 24 sales worth $30.84 million and no purchases. The newest one on file is from May 18, 2026 (Tariq Musa, Director).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 18, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| BlackRock Advisors LLC | 7.0 million | 5.24% | $1.1B |
| T. Rowe Price International Ltd. | 6.5 million | 4.86% | $1.0B |
| Vanguard Capital Management LLC | 5.8 million | 4.29% | $915.0M |
| Fidelity Management & Research Co. LLC | 5.5 million | 4.08% | $871.0M |
| Vanguard Portfolio Management LLC | 5.4 million | 4.06% | $866.0M |
| Invesco Advisers, Inc. | 4.4 million | 3.30% | $704.0M |
| Goldman Sachs Wealth Services LP | 3.8 million | 2.81% | $600.0M |
| Two Sigma Investments LP | 3.7 million | 2.77% | $591.0M |
| Capital Research & Management Co. (International Investors) | 3.4 million | 2.53% | $541.0M |
| Deep Track Capital LP | 3.4 million | 2.53% | $540.0M |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 629 | – | $20.2B |
| Q1 2026 | 513 | 135.0 million | $12.5B |
| Q4 2025 | 532 | 134.0 million | $13.7B |
| Q3 2025 | 429 | 124.0 million | $7.7B |
| Q2 2025 | 401 | 126.0 million | $6.5B |
| Q1 2025 | 372 | 120.0 million | $5.1B |
| Q4 2024 | 327 | 120.0 million | $3.7B |
| Q3 2024 | 308 | 128.0 million | $2.9B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Tariq Musa | May 18, 2026 | Director | Sale at price 95.96 per share. | $11,131 |
| Tariq Musa | May 15, 2026 | Director | -- | – |
| Talasaz Amirali | May 12, 2026 | Chief Executive Officer | Sale at price 100.32 per share. | $5.0M |
| Krognes Steve E | Apr 30, 2026 | Director | -- | – |
| Mignone Roberto A. | Apr 21, 2026 | Director | -- | – |
| Hidalgo Medina Manuel | Apr 17, 2026 | Director | -- | – |
| Tariq Musa | Apr 16, 2026 | Director | Sale at price 84.83 per share. | $9,840 |
| Tariq Musa | Apr 15, 2026 | Director | -- | – |
| Saia John Gomes | Apr 15, 2026 | Officer | -- | – |
| Monroe Terilyn J | Apr 6, 2026 | Officer | Sale at price 92.68 per share. | $355,150 |
| Eagle Craig | Apr 1, 2026 | Officer | -- | – |
| Chudova Darya | Apr 1, 2026 | Chief Technology Officer | -- | – |
Newest 12 of 100 insider transactions in the last two years.
BlackRock Advisors LLC, with 5.24% of the company (as of September 25, 2026). Next: T. Rowe Price International Ltd. (4.86%) and Vanguard Capital Management LLC (4.29%).
629 institutional holdings reports listed Guardant Health shares in Q2 2026 worth $20.20 billion.
In the last two years insiders reported 24 sales and no purchases (100 transactions in all); the newest on file is from May 18, 2026.