The largest holder of Illumina stock is Capital Research & Management Co. (World Investors), with 15.4 million shares (10.22% of the company), worth about $3.30 billion as of September 25, 2026. The 10 largest holders together own 47.5%.
In Q2 2026, 977 institutional holdings reports listed shares worth $27.70 billion.
Insiders reported 54 transactions in the last two years: 6 sales worth $48.57 million and 4 purchases. The newest one on file is from May 14, 2026 (Meister Keith A, Director).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 14, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| Capital Research & Management Co. (World Investors) | 15.4 million | 10.22% | $3.3B |
| BlackRock Advisors LLC | 15.2 million | 10.09% | $3.3B |
| Vanguard Portfolio Management LLC | 6.6 million | 4.39% | $1.4B |
| Vanguard Capital Management LLC | 6.6 million | 4.36% | $1.4B |
| State Street Corporation | 6.5 million | 4.31% | $1.4B |
| WCM Investment Management LLC | 6.2 million | 4.11% | $1.3B |
| Fidelity Management & Research Co. LLC | 4.5 million | 2.98% | $961.0M |
| AQR Capital Management LLC | 3.5 million | 2.35% | $757.0M |
| BlackRock Life Ltd. | 3.5 million | 2.33% | $751.0M |
| PRIMECAP Management Co. | 3.5 million | 2.33% | $751.0M |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 977 | – | $27.7B |
| Q1 2026 | 885 | 157.0 million | $19.3B |
| Q4 2025 | 911 | 158.0 million | $20.8B |
| Q3 2025 | 829 | 158.0 million | $15.0B |
| Q2 2025 | 786 | 157.0 million | $14.9B |
| Q1 2025 | 772 | 155.0 million | $12.3B |
| Q4 2024 | 916 | 155.0 million | $20.6B |
| Q3 2024 | 862 | 144.0 million | $18.8B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Meister Keith A | May 14, 2026 | Director | Sale at price 144.13 - 148.14 per share. | $47.9M |
| Meister Keith A | May 12, 2026 | Director | Conversion of Exercise of derivative security at price 102.82 per share. | $26.3M |
| Meister Keith A | May 11, 2026 | Director | Conversion of Exercise of derivative security at price 102.82 per share. | $9.1M |
| Wedel Christensen Jakob | May 6, 2026 | Officer | Sale at price 139.04 per share. | $97,328 |
| Ullem Scott B | Mar 31, 2026 | Director | Stock Award(Grant) at price 131.55 per share. | $24,994 |
| Meister Keith A | Mar 31, 2026 | Director | Stock Award(Grant) at price 131.55 per share. | $21,179 |
| Pegels Kevin Carl | Mar 5, 2026 | Officer | Stock Award(Grant) at price 128.24 per share. | $810,092 |
| Ericksen Scott D | Mar 5, 2026 | Officer | Stock Award(Grant) at price 128.24 per share. | $412,548 |
| Barnard Steven | Mar 5, 2026 | Chief Technology Officer | Stock Award(Grant) at price 128.24 per share. | $975,009 |
| Leckman Patricia | Mar 5, 2026 | Officer | Stock Award(Grant) at price 128.24 per share. | $810,092 |
| Wedel Christensen Jakob | Mar 5, 2026 | Officer | Stock Award(Grant) at price 128.24 per share. | $720,068 |
| Dhingra Ankur | Mar 5, 2026 | Chief Financial Officer | Stock Award(Grant) at price 128.24 per share. | $1.2M |
Newest 12 of 54 insider transactions in the last two years.
Capital Research & Management Co. (World Investors), with 10.22% of the company (as of September 25, 2026). Next: BlackRock Advisors LLC (10.09%) and Vanguard Portfolio Management LLC (4.39%).
977 institutional holdings reports listed Illumina shares in Q2 2026 worth $27.70 billion.
In the last two years insiders reported 6 sales and 4 purchases (54 transactions in all); the newest on file is from May 14, 2026.