Summit Therapeutics Inc. (SMMT) Shareholders & Insider Trades

Executive TeamFinancialsShareholders

Summit Therapeutics shareholders at a glance

The largest holder of Summit Therapeutics stock is Robert Duggan73.22 %, with 584.1 million shares (73.22% of the company), worth about $7.96 billion as of September 25, 2026. The 10 largest holders together own 90.1%.

In Q2 2026, 272 institutional holdings reports listed 136.0 million shares worth $1.98 billion, up 14.3% in shares from Q1 2026.

Insiders reported 13 transactions in the last two years: no sales and 5 purchases. The newest one on file is from October 21, 2025 (Duggan Robert William, Chief Executive Officer).

Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through October 21, 2025.

SMMT logo

Summit Therapeutics Inc.

SMMTUnited States
Healthcare

Shareholders Summary

2026Q2

Filings
272
Options Value
$98.30M
Value (excl. Options)
$1.98B
Shares (excl. Options)
136.00M

Ownership by Type

Geographic Distribution

Largest Summit Therapeutics shareholders

HolderShares% of companyValue
Robert Duggan73.22 %584.1 million73.22%$8.0B
Baker Bros. Advisors LP32.8 million4.11%$447.0M
Michelle Xia4.018 %32.1 million4.02%$437.0M
Mahkam Zanganeh3.251 %25.9 million3.25%$353.0M
Fidelity Management & Research Co. LLC10.0 million1.26%$137.0M
State Street Corporation9.5 million1.20%$130.0M
BlackRock Advisors LLC8.5 million1.07%$116.0M
Vanguard Capital Management LLC5.7 million0.72%$78.0M
UBS Financial Services, Inc.5.2 million0.66%$71.0M
Vanguard Portfolio Management LLC5.0 million0.63%$69.0M

As of September 25, 2026.

Summit Therapeutics institutional holdings by quarter

QuarterReportsSharesValue
Q2 2026272136.0 million$2.0B
Q1 2026242119.0 million$2.3B
Q4 2025225118.0 million$2.1B
Q3 2025261103.0 million$2.1B
Q2 202525698.1 million$2.1B
Q1 202523699.0 million$1.9B
Q4 202423492.6 million$1.7B
Q3 202419884.6 million$1.9B

Shares and value held by institutions that file quarterly holdings reports (options not included).

Summit Therapeutics insider trades

InsiderDateTitleTransactionValue
Duggan Robert WilliamOct 21, 2025Chief Executive OfficerStock Award(Grant) at price 18.74 per share.$267.0M
Zanganeh MahkamOct 21, 2025Chief Executive OfficerStock Award(Grant) at price 18.74 per share.$267.0M
Soni Manmeet SinghOct 21, 2025Chief Operating OfficerStock Award(Grant) at price 18.74 per share.$999,985
Anand BhaskarOct 21, 2025OfficerStock Award(Grant) at price 18.74 per share.$499,983
Duggan Robert WilliamOct 21, 2025Chief Executive OfficerPurchase at price 18.74 per share.$499,983
Zanganeh MahkamOct 21, 2025Chief Executive OfficerPurchase at price 18.74 per share.$499,983
Xia YuOct 21, 2025DirectorPurchase at price 18.74 per share.$10.0M
Duggan Robert WilliamSep 11, 2025Chief Executive OfficerPurchase at price 17.68 - 18.07 per share.$6.0M
Zanganeh MahkamSep 11, 2025Chief Executive OfficerPurchase at price 17.68 - 18.07 per share.$6.0M
Duggan Robert WilliamMay 30, 2025Chief Executive OfficerConversion of Exercise of derivative security at price 2.64 per share.$196,799
Zanganeh MahkamMay 30, 2025Chief Executive OfficerConversion of Exercise of derivative security at price 2.64 per share.$196,799
Duggan Robert WilliamApr 8, 2025Chief Executive OfficerConversion of Exercise of derivative security at price 1.58 per share.$6.3M

Newest 12 of 13 insider transactions in the last two years.

Questions and answers

Who owns the most Summit Therapeutics stock?

Robert Duggan73.22 %, with 73.22% of the company (as of September 25, 2026). Next: Baker Bros. Advisors LP (4.11%) and Michelle Xia4.018 % (4.02%).

How many institutions own Summit Therapeutics stock?

272 institutional holdings reports listed Summit Therapeutics shares in Q2 2026, 136.0 million shares in all worth $1.98 billion.

Are Summit Therapeutics insiders buying or selling the stock?

In the last two years insiders reported no sales and 5 purchases (13 transactions in all); the newest on file is from October 21, 2025.

Disclaimer: This analysis is for informational and educational purposes only and does not constitute financial, investment, tax, or legal advice. Data may be incomplete, delayed, or contain inaccuracies. Consult with a qualified financial advisor before making any investment decisions.
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