The largest holder of Exelixis stock is BlackRock Advisors LLC, with 26.8 million shares (10.66% of the company), worth about $1.46 billion as of September 25, 2026. The 10 largest holders together own 51.2%.
In Q2 2026, 785 institutional holdings reports listed shares worth $14.40 billion.
Insiders reported 89 transactions in the last two years: 33 sales worth $63.41 million and 1 purchase. The newest one on file is from May 7, 2026 (Beckerle Mary C, Director).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 7, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| BlackRock Advisors LLC | 26.8 million | 10.66% | $1.5B |
| Farallon Capital Management LLC | 14.0 million | 5.57% | $764.0M |
| Farallon Capital Management LLC | 13.5 million | 5.36% | $736.0M |
| Renaissance Technologies LLC | 13.4 million | 5.34% | $734.0M |
| Vanguard Portfolio Management LLC | 12.0 million | 4.79% | $658.0M |
| AQR Capital Management LLC | 11.0 million | 4.39% | $602.0M |
| Vanguard Capital Management LLC | 11.0 million | 4.36% | $598.0M |
| State Street Corporation | 10.0 million | 3.97% | $545.0M |
| Fuller & Thaler Asset Management, Inc. | 8.9 million | 3.55% | $488.0M |
| LSV Asset Management | 8.1 million | 3.24% | $445.0M |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 785 | – | $14.4B |
| Q1 2026 | 723 | 259.0 million | $11.1B |
| Q4 2025 | 714 | – | $11.8B |
| Q3 2025 | 657 | 252.0 million | $10.4B |
| Q2 2025 | 663 | 257.0 million | $11.3B |
| Q1 2025 | 588 | 255.0 million | $9.4B |
| Q4 2024 | 548 | 252.0 million | $8.4B |
| Q3 2024 | 490 | 255.0 million | $6.6B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Beckerle Mary C | May 7, 2026 | Director | Sale at price 48.45 per share. | $373,646 |
| Freire Maria C | May 7, 2026 | Director | Sale at price 46.00 per share. | $949,164 |
| Poste George H | May 7, 2026 | Director | Sale at price 45.71 per share. | $2.7M |
| Beckerle Mary C | May 7, 2026 | Director | Conversion of Exercise of derivative security at price 23.24 per share. | $89,613 |
| Freire Maria C | May 7, 2026 | Director | Conversion of Exercise of derivative security at price 19.77 per share. | $407,934 |
| Aftab T Dana | Feb 26, 2026 | Officer | Stock Award(Grant) at price 0.00 per share. | – |
| Hefti Brenda | Feb 26, 2026 | General Counsel | Stock Award(Grant) at price 0.00 per share. | – |
| Senner Christopher J. | Feb 26, 2026 | Chief Financial Officer | Stock Award(Grant) at price 0.00 per share. | – |
| Haley Patrick Joseph | Feb 26, 2026 | Officer | Stock Award(Grant) at price 0.00 per share. | – |
| Morrissey Michael M | Feb 26, 2026 | Chief Executive Officer | Stock Award(Grant) at price 0.00 per share. | – |
| Morrissey Michael M | Feb 24, 2026 | Chief Executive Officer | Stock Gift at price 0.00 per share. | – |
| Aftab T Dana | Feb 24, 2026 | Officer | Sale at price 44.50 per share. | $2.1M |
Newest 12 of 89 insider transactions in the last two years.
BlackRock Advisors LLC, with 10.66% of the company (as of September 25, 2026). Next: Farallon Capital Management LLC (5.57%) and Farallon Capital Management LLC (5.36%).
785 institutional holdings reports listed Exelixis shares in Q2 2026 worth $14.40 billion.
In the last two years insiders reported 33 sales and 1 purchase (89 transactions in all); the newest on file is from May 7, 2026.