The largest holder of Vertex Pharmaceuticals stock is Capital Research & Management Co. (World Investors), with 26.1 million shares (10.30% of the company), worth about $14.22 billion as of September 25, 2026. The 10 largest holders together own 48.5%.
In Q2 2026, 1,839 institutional holdings reports listed shares worth $121.00 billion.
Insiders reported 100 transactions in the last two years: 58 sales worth $93.25 million and 2 purchases. The newest one on file is from May 12, 2026 (Bozic Carmen, Officer).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through May 12, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| Capital Research & Management Co. (World Investors) | 26.1 million | 10.30% | $14.2B |
| Capital Research & Management Co. (Global Investors) | 19.5 million | 7.69% | $10.6B |
| BlackRock Advisors LLC | 17.6 million | 6.93% | $9.6B |
| Vanguard Capital Management LLC | 16.6 million | 6.54% | $9.0B |
| State Street Corporation | 11.9 million | 4.68% | $6.5B |
| Invesco Advisers, Inc. | 8.0 million | 3.17% | $4.4B |
| JPMorgan Investment Management, Inc. | 6.5 million | 2.57% | $3.5B |
| Geode Capital Management LLC | 6.0 million | 2.37% | $3.3B |
| BlackRock Life Ltd. | 6.0 million | 2.35% | $3.3B |
| Vanguard Portfolio Management LLC | 4.9 million | 1.93% | $2.7B |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 1,839 | – | $121.0B |
| Q1 2026 | 1,775 | 238.0 million | $106.0B |
| Q4 2025 | 1,753 | 242.0 million | $110.0B |
| Q3 2025 | 1,607 | 239.0 million | $93.4B |
| Q2 2025 | 1,653 | 243.0 million | $108.0B |
| Q1 2025 | 1,704 | 241.0 million | $117.0B |
| Q4 2024 | 1,660 | 237.0 million | $95.4B |
| Q3 2024 | 1,644 | 243.0 million | $113.0B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Bozic Carmen | May 12, 2026 | Officer | Sale at price 450.00 per share. | $3.1M |
| Bhatia Sangeeta N | May 4, 2026 | Director | Sale at price 423.73 per share. | $134,746 |
| Thornberry Nancy A. | May 1, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Bhatia Sangeeta N | May 1, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Mckenzie Diana L | May 1, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Schneider Jennifer J | May 1, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Garber Alan M | May 1, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Liu Joy | May 1, 2026 | Officer | Sale at price 425.02 per share. | $469,222 |
| Liu Joy | Apr 1, 2026 | Officer | Sale at price 449.17 per share. | $439,288 |
| Bozic Carmen | Mar 27, 2026 | Officer | Sale at price 450.95 per share. | $1.1M |
| Bozic Carmen | Mar 13, 2026 | Officer | Sale at price 481.79 per share. | $1.1M |
| Mckechnie Duncan | Mar 11, 2026 | Officer | Sale at price 498.42 per share. | $1.3M |
Newest 12 of 100 insider transactions in the last two years.
Capital Research & Management Co. (World Investors), with 10.30% of the company (as of September 25, 2026). Next: Capital Research & Management Co. (Global Investors) (7.69%) and BlackRock Advisors LLC (6.93%).
1,839 institutional holdings reports listed Vertex Pharmaceuticals shares in Q2 2026 worth $121.00 billion.
In the last two years insiders reported 58 sales and 2 purchases (100 transactions in all); the newest on file is from May 12, 2026.