Medicare prescription drug plans, 2024. Official US government data.
Drug cost
$288B
2024
Prescriptions
1.71B
Claims, including refills
Prescribers
1,416,883
With published claims
Brand drugs
72%
Share of cost
Eliquis (Apixaban) had the highest Medicare prescription drug cost in 2024: $20.77B for 24,054,695 prescriptions and refills, written by 556,431 prescribers for 4,423,497 patients.
Medicare drug plans paid $288B for 1.71B prescriptions written by 1,416,883 prescribers in 2024, 4.6% more than in 2023. Brand drugs were 72% of the cost. These amounts are before the rebates drug makers pay the plans.
The 10 drugs with the highest cost made up $82.27B, or 29% of Medicare prescription drug cost in 2024.
Prescriber data, all drugs
All plans and drugs, by year
Click a drug for its prescribers, states, spending by year and maker
| # | Drug | Cost | Claims | Patients | Cost per claim | Company |
|---|---|---|---|---|---|---|
| 1 | Eliquis Apixaban | $20.77B | 24.1M | 4.4M | $863.42 | BMY |
| 2 | Ozempic Semaglutide | $12.97B | 10.4M | 2.0M | $1,245.09 | NVO |
| 3 | Jardiance Empagliflozin | $11.43B | 11.4M | 2.5M | $1,005.97 | - |
| 4 | Mounjaro Tirzepatide | $6.33B | 5.1M | 894K | $1,241.24 | LLY |
| 5 | Xarelto Rivaroxaban | $6.23B | 6.7M | 1.3M | $935.73 | JNJ |
| 6 | Trulicity Dulaglutide | $5.45B | 4.3M | 788K | $1,266.91 | LLY |
| 7 | Trelegy Ellipta Fluticasone/Umeclidin/Vilanter | $5.29B | 6.2M | 1.3M | $847.00 | GSK |
| 8 | Farxiga Dapagliflozin Propanediol | $5.29B | 5.6M | 1.3M | $938.93 | AZN |
| 9 | Humira(Cf) Pen Adalimumab | $4.33B | 490K | 64K | $8,828.43 | - |
| 10 | Revlimid Lenalidomide | $4.18B | 240K | 39K | $17,426.30 | BMY |
| 11 | Entresto Sacubitril/Valsartan | $4.02B | 3.9M | 795K | $1,031.18 | NVS |
| 12 | Januvia Sitagliptin Phosphate | $3.81B | 4.0M | 828K | $945.51 | MRK |
| 13 | Biktarvy Bictegrav/Emtricit/Tenofov Ala | $3.45B | 840K | 92K | $4,110.59 | GILD |
| 14 | Xtandi Enzalutamide | $3.40B | 256K | 35K | $13,301.42 | 4503.T |
| 15 | Stelara Ustekinumab | $3.38B | 133K | 25K | $25,424.15 | - |
| 16 | Vyndamax Tafamidis | $2.83B | 109K | 14K | $25,882.18 | PFE |
| 17 | Lenalidomide Generic | $2.64B | 198K | 30K | $13,334.05 | - |
| 18 | Enbrel Sureclick Etanercept | $2.34B | 296K | 39K | $7,895.06 | AMGN |
| 19 | Myrbetriq Mirabegron | $2.30B | 3.5M | 763K | $665.20 | 4503.T |
| 20 | Imbruvica Ibrutinib | $2.27B | 146K | 15K | $15,477.88 | ABBV |
| 21 | Pomalyst Pomalidomide | $2.15B | 99K | 14K | $21,796.49 | BMY |
| 22 | Ofev Nintedanib Esylate | $2.09B | 162K | 24K | $12,901.81 | - |
| 23 | Jakafi Ruxolitinib Phosphate | $2.08B | 131K | 16K | $15,913.06 | INCY |
| 24 | Ibrance Palbociclib | $2.03B | 131K | 16K | $15,470.96 | PFE |
| 25 | Linzess Linaclotide | $1.98B | 2.5M | 632K | $790.72 | ABBV |
| 26 | Ingrezza Valbenazine Tosylate | $1.96B | 255K | 32K | $7,676.11 | NBIX |
| 27 | Rybelsus Semaglutide | $1.89B | 1.3M | 310K | $1,509.98 | NVO |
| 28 | Invega Sustenna Paliperidone Palmitate | $1.88B | 624K | 72K | $3,005.60 | JNJ |
| 29 | Dupixent Pen Dupilumab | $1.80B | 450K | 66K | $4,005.63 | SNY |
| 30 | Skyrizi Pen Risankizumab-Rzaa | $1.78B | 86K | 27K | $20,782.05 | ABBV |
| 31 | Brukinsa Zanubrutinib | $1.72B | 131K | 18K | $13,185.70 | ONC |
| 32 | Repatha Sureclick Evolocumab | $1.71B | 1.9M | 382K | $879.45 | AMGN |
| 33 | Calquence Acalabrutinib Maleate | $1.70B | 122K | 15K | $13,909.86 | AZN |
| 34 | Tagrisso Osimertinib Mesylate | $1.63B | 96K | 12K | $16,878.65 | AZN |
| 35 | Creon Lipase/Protease/Amylase | $1.49B | 775K | 185K | $1,926.86 | ABBV |
| 36 | Erleada Apalutamide | $1.39B | 96K | 13K | $14,504.16 | JNJ |
| 37 | Rinvoq Upadacitinib | $1.39B | 194K | 29K | $7,146.72 | ABBV |
| 38 | Breo Ellipta Fluticasone/Vilanterol | $1.36B | 2.6M | 596K | $519.83 | GSK |
| 39 | Restasis Cyclosporine | $1.29B | 1.4M | 472K | $947.62 | ABBV |
| 40 | Opsumit Macitentan | $1.23B | 97K | 11K | $12,679.17 | JNJ |
| 41 | Cabometyx Cabozantinib S-Malate | $1.22B | 50K | 9,180 | $24,221.62 | EXEL |
| 42 | Xifaxan Rifaximin | $1.16B | 417K | 105K | $2,779.27 | BHC |
| 43 | Vraylar Cariprazine Hcl | $1.14B | 767K | 118K | $1,481.08 | ABBV |
| 44 | Breztri Aerosphere Budesonide/Glycopyr/Formoterol | $1.13B | 1.4M | 367K | $789.66 | AZN |
| 45 | Tradjenta Linagliptin | $1.13B | 1.4M | 274K | $779.34 | - |
| 46 | Austedo Deutetrabenazine | $1.07B | 162K | 18K | $6,576.93 | TEVA |
| 47 | Verzenio Abemaciclib | $1.06B | 72K | 11K | $14,690.96 | LLY |
| 48 | Otezla Apremilast | $1.04B | 213K | 31K | $4,896.91 | AMGN |
| 49 | Nubeqa Darolutamide | $998.1M | 78K | 12K | $12,783.10 | BAYN.DE |
| 50 | Tresiba Flextouch U-200 Insulin Degludec | $973.7M | 894K | 217K | $1,089.65 | NVO |
| 51 | Gemtesa Vibegron | $944.7M | 1.4M | 320K | $694.01 | 4506.T |
| 52 | Venclexta Venetoclax | $941.7M | 108K | 22K | $8,730.12 | ABBV |
| 53 | Uptravi Selexipag | $908.4M | 39K | 4,318 | $23,071.34 | - |
| 54 | Spiriva Respimat Tiotropium Bromide | $876.9M | 1.3M | 327K | $687.45 | - |
| 55 | Lenvima Lenvatinib Mesylate | $875.4M | 37K | 8,447 | $23,577.29 | 4523.T |
| 56 | Rexulti Brexpiprazole | $861.1M | 598K | 95K | $1,439.20 | 4578.T |
| 57 | Tresiba Flextouch U-100 Insulin Degludec | $825.6M | 1.3M | 339K | $644.19 | NVO |
| 58 | Anoro Ellipta Umeclidinium Brm/Vilanterol Tr | $819.1M | 1.4M | 291K | $591.96 | GSK |
| 59 | Cosentyx Sensoready (2 Pens) Secukinumab | $817.4M | 102K | 14K | $7,980.93 | NVS |
| 60 | Shingrix Varicella-Zoster Ge/As01b/Pf | $775.3M | 3.9M | 2.9M | $196.56 | GSK |
| 61 | Kisqali Ribociclib Succinate | $775.1M | 53K | 8,777 | $14,749.11 | NVS |
| 62 | Arexvy Rsvpref3 Antigen/As01e/Pf | $773.9M | 2.8M | 2.8M | $272.99 | GSK |
| 63 | Prolia Denosumab | $771.5M | 451K | 285K | $1,711.93 | AMGN |
| 64 | Epclusa Sofosbuvir/Velpatasvir | $757.7M | 31K | 12K | $24,117.11 | GILD |
| 65 | Atorvastatin Calcium Generic | $756.3M | 73.3M | 17.8M | $10.31 | - |
| 66 | Tyvaso Dpi Treprostinil | $728.7M | 30K | 4,384 | $24,031.51 | UTHR |
| 67 | Trikafta Elexacaftor/Tezacaftor/Ivacaft | $724.0M | 27K | 2,728 | $26,569.05 | VRTX |
| 68 | Vascepa Icosapent Ethyl | $723.9M | 1.5M | 301K | $490.98 | AMRN |
| 69 | Oxervate Cenegermin-Bkbj | $714.5M | 18K | 4,781 | $39,059.22 | - |
| 70 | Janumet Sitagliptin Phos/Metformin Hcl | $709.0M | 744K | 159K | $953.32 | MRK |
| 71 | Lantus Solostar Insulin Glargine,hum.Rec.Anlog | $698.9M | 5.6M | 1.4M | $125.50 | SNY |
| 72 | Humira Pen Adalimumab | $697.1M | 85K | 12K | $8,187.97 | ABBV |
| 73 | Adempas Riociguat | $693.9M | 51K | 5,551 | $13,653.43 | BAYN.DE |
| 74 | Abiraterone Acetate Generic | $692.8M | 389K | 55K | $1,779.56 | - |
| 75 | Dupixent Syringe Dupilumab | $686.8M | 171K | 23K | $4,021.06 | SNY |
| 76 | Brilinta Ticagrelor | $685.3M | 1.0M | 243K | $666.17 | AZN |
| 77 | Promacta Eltrombopag Olamine | $672.3M | 46K | 6,663 | $14,665.16 | NVS |
| 78 | Basaglar Kwikpen U-100 Insulin Glargine,hum.Rec.Anlog | $664.4M | 1.8M | 423K | $373.87 | LLY |
| 79 | Nuplazid Pimavanserin Tartrate | $657.6M | 143K | 17K | $4,589.56 | ACAD |
| 80 | Lumigan Bimatoprost | $647.0M | 1.4M | 337K | $459.66 | ABBV |
| 81 | Abilify Maintena Aripiprazole | $643.5M | 235K | 30K | $2,738.86 | 4578.T |
| 82 | Enbrel Etanercept | $632.3M | 81K | 11K | $7,827.79 | AMGN |
| 83 | Tivicay Dolutegravir Sodium | $629.2M | 256K | 29K | $2,461.15 | GSK |
| 84 | Nurtec Odt Rimegepant Sulfate | $625.0M | 427K | 105K | $1,465.42 | PFE |
| 85 | Tremfya Guselkumab | $618.5M | 46K | 11K | $13,428.48 | - |
| 86 | Symbicort Budesonide/Formoterol Fumarate | $597.6M | 1.9M | 588K | $312.39 | AZN |
| 87 | Zenpep Lipase/Protease/Amylase | $597.1M | 259K | 58K | $2,304.81 | - |
| 88 | Austedo Xr Deutetrabenazine | $596.6M | 82K | 11K | $7,317.03 | TEVA |
| 89 | Lynparza Olaparib | $593.6M | 41K | 7,012 | $14,330.18 | AZN |
| 90 | Xeljanz Xr Tofacitinib Citrate | $589.6M | 94K | 13K | $6,251.85 | PFE |
| 91 | Kesimpta Pen Ofatumumab | $582.5M | 60K | 7,187 | $9,713.94 | NVS |
| 92 | Gammagard Liquid Immun Glob G(Igg)/Gly/Iga Ov50 | $580.5M | 56K | 4,677 | $10,448.45 | TAK |
| 93 | Orencia Clickject Abatacept | $570.0M | 95K | 14K | $6,025.95 | BMY |
| 94 | Triumeq Abacavir/Dolutegravir/Lamivudi | $565.7M | 143K | 16K | $3,952.48 | GSK |
| 95 | Taltz Autoinjector Ixekizumab | $564.4M | 74K | 10K | $7,636.46 | LLY |
| 96 | Toujeo Max Solostar Insulin Glargine,hum.Rec.Anlog | $560.9M | 514K | 134K | $1,091.57 | SNY |
| 97 | Albuterol Sulfate Hfa Albuterol Sulfate | $552.4M | 18.6M | 6.7M | $29.73 | - |
| 98 | Genvoya Elviteg/Cob/Emtri/Tenof Alafen | $551.6M | 131K | 15K | $4,200.06 | GILD |
| 99 | Toujeo Solostar Insulin Glargine,hum.Rec.Anlog | $549.8M | 763K | 189K | $720.87 | SNY |
| 100 | Invega Trinza Paliperidone Palmitate | $549.4M | 64K | 19K | $8,602.13 | JNJ |
Search every drug, prescriber and state in the Prescriptions tab, or see Medicare hospital stays by diagnosis group.
Official US government data on Medicare prescription drug plans (Part D), published once a year. Cost is what the plans, patients and others paid at the pharmacy, before manufacturer rebates. Drugs with fewer than 11 claims for a prescriber are not published. Company links come from a reviewed list of drug makers.