The largest holder of AstraZeneca stock is Investor AB (Investment Company), with 51.6 million shares (3.33% of the company), worth about $8.38 billion as of September 25, 2026. The 10 largest holders together own 21.3%.
In Q2 2026, 28 institutional holdings reports listed 833,000 shares worth $158.00 million, down 5.3% in shares from Q1 2026.
Insiders reported 69 transactions in the last two years: no sales and no purchases. The newest one on file is from September 14, 2026 (Soriot (Pascal), --).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through September 14, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| Investor AB (Investment Company) | 51.6 million | 3.33% | $8.4B |
| Vanguard Capital Management LLC | 45.4 million | 2.93% | $7.4B |
| Capital Research & Management Co. (International Investors) | 34.6 million | 2.23% | $5.6B |
| Norges Bank (13F) | 33.9 million | 2.18% | $5.5B |
| Vanguard Fiduciary Trust Co. | 33.2 million | 2.14% | $5.4B |
| Capital Research & Management Co. (World Investors) | 30.1 million | 1.94% | $4.9B |
| Fidelity Management & Research Co. LLC | 28.9 million | 1.86% | $4.7B |
| Wellington Trust Co., NA | 28.5 million | 1.84% | $4.6B |
| Legal & General Investment Management Ltd. | 25.8 million | 1.66% | $4.2B |
| JPMorgan Investment Management, Inc. | 19.2 million | 1.24% | $3.1B |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 28 | 833,000 | $158.0M |
| Q1 2026 | 66 | 880,000 | $162.0M |
| Q4 2025 | 1,419 | 503.0 million | $46.3B |
| Q3 2025 | 1,349 | 499.0 million | $38.3B |
| Q2 2025 | 1,276 | 501.0 million | $35.1B |
| Q1 2025 | 1,310 | 508.0 million | $37.8B |
| Q4 2024 | 1,269 | 515.0 million | $33.7B |
| Q3 2024 | 1,291 | 506.0 million | $39.4B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Soriot (Pascal) | Sep 14, 2026 | -- | Bought at price 161.57 per share. | $9.7M |
| Sarin (Aradhana M.D.) | Sep 14, 2026 | -- | -- | – |
| Demare (Michel) | Sep 14, 2026 | -- | Bought at price 161.83 per share. | $404,567 |
| Sarin (Aradhana M.D.) | Aug 17, 2026 | -- | -- | – |
| Soriot (Pascal) | May 14, 2026 | -- | -- | – |
| Soriot (Pascal) | Mar 5, 2026 | -- | -- | – |
| Soriot (Pascal) | Mar 4, 2026 | -- | -- | – |
| Sarin (Aradhana M.D.) | Mar 4, 2026 | -- | -- | – |
| Investor Ab | Jan 31, 2026 | -- | -- | – |
| Blackrock Financial Management, Inc. | Jan 31, 2026 | -- | -- | – |
| The Capital Group Companies, Inc. | Jan 31, 2026 | -- | -- | – |
| Wellington Management Company, L.L.P. | Jan 31, 2026 | -- | -- | – |
Newest 12 of 69 insider transactions in the last two years.
Investor AB (Investment Company), with 3.33% of the company (as of September 25, 2026). Next: Vanguard Capital Management LLC (2.93%) and Capital Research & Management Co. (International Investors) (2.23%).
28 institutional holdings reports listed AstraZeneca shares in Q2 2026, 833,000 shares in all worth $158.00 million.
In the last two years insiders reported no sales and no purchases (69 transactions in all); the newest on file is from September 14, 2026.