The largest holder of Amgen stock is BlackRock Advisors LLC, with 36.7 million shares (6.79% of the company), worth about $15.77 billion as of September 25, 2026. The 10 largest holders together own 40.4%.
In Q2 2026, 3,277 institutional holdings reports listed shares worth $163.00 billion.
Insiders reported 108 transactions in the last two years: 17 sales worth $53.73 million and no purchases. The newest one on file is from August 13, 2026 (Khosla Rachna, Officer).
Major holders as of September 25, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through August 13, 2026.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| BlackRock Advisors LLC | 36.7 million | 6.79% | $15.8B |
| Vanguard Capital Management LLC | 35.3 million | 6.52% | $15.2B |
| State Street Corporation | 30.6 million | 5.65% | $13.1B |
| Capital Research & Management Co. (World Investors) | 29.1 million | 5.38% | $12.5B |
| Invesco Advisers, Inc. | 16.3 million | 3.02% | $7.0B |
| Geode Capital Management LLC | 15.7 million | 2.90% | $6.7B |
| Charles Schwab Investment Management, Inc. | 15.0 million | 2.78% | $6.5B |
| Vanguard Portfolio Management LLC | 14.9 million | 2.75% | $6.4B |
| Eaton Vance Management | 13.7 million | 2.53% | $5.9B |
| Ishares (DE) InvAG mit Teilgesellschaftsvermogen | 11.5 million | 2.12% | $4.9B |
As of September 25, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 3,277 | – | $163.0B |
| Q1 2026 | 3,265 | 440.0 million | $154.0B |
| Q4 2025 | 3,223 | 451.0 million | $147.0B |
| Q3 2025 | 2,966 | 427.0 million | $121.0B |
| Q2 2025 | 2,996 | 438.0 million | $122.0B |
| Q1 2025 | 3,073 | 429.0 million | $134.0B |
| Q4 2024 | 3,006 | 419.0 million | $109.0B |
| Q3 2024 | 2,965 | 419.0 million | $135.0B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Khosla Rachna | Aug 13, 2026 | Officer | Sale at price 412.57 - 416.43 per share. | $1.3M |
| Khosla Rachna | Aug 13, 2026 | Officer | Conversion of Exercise of derivative security at price 162.60 per share. | $203,575 |
| Busch Matthew C. | Aug 7, 2026 | Officer | Stock Award(Grant) at price 0.00 per share. | – |
| Drake Michael V | Aug 7, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Ishrak Omar Syed | Aug 7, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Holley Charles M Jr | Aug 7, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Grygiel Nancy A | Aug 6, 2026 | Officer | Sale at price 402.16 per share. | $1.2M |
| Miller Derek | Aug 6, 2026 | Officer | Sale at price 402.54 per share. | $1.6M |
| Grygiel Nancy A | Aug 6, 2026 | Officer | Conversion of Exercise of derivative security at price 177.31 - 177.46 per share. | $526,906 |
| Miller Derek | Aug 6, 2026 | Officer | Conversion of Exercise of derivative security at price 162.60 - 177.46 per share. | $659,574 |
| Klotman Mary E | May 19, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
| Drake Michael V | May 19, 2026 | Director | Stock Award(Grant) at price 0.00 per share. | – |
Newest 12 of 108 insider transactions in the last two years.
BlackRock Advisors LLC, with 6.79% of the company (as of September 25, 2026). Next: Vanguard Capital Management LLC (6.52%) and State Street Corporation (5.65%).
3,277 institutional holdings reports listed Amgen shares in Q2 2026 worth $163.00 billion.
In the last two years insiders reported 17 sales and no purchases (108 transactions in all); the newest on file is from August 13, 2026.