Exelixis reported revenue of $2.32 billion for fiscal year 2025 (ended December 31, 2025), up 7.0% from fiscal year 2024. Net income was $782.57 million, a net margin of 33.7%, and diluted earnings per share were $2.78.
At the end of fiscal year 2025 it had total assets of $2.84 billion, total liabilities of $683.10 million and shareholders' equity of $2.16 billion, with cash and short-term investments of $1.06 billion and total debt of $173.04 million.
Its operations brought in $884.27 million of cash; capital spending was $39.93 million, leaving free cash flow of $844.34 million.
The tables below show the income statement, balance sheet and cash flow statement; the key figures of the last 5 fiscal years are at the bottom of the page.
Figures from company filings, in USD; latest fiscal year ended December 31, 2025.

Annual • USD
| FY2025 | FY2024 | FY2023 | FY2022 | FY2021 | |
|---|---|---|---|---|---|
| Revenue | $2.3B | $2.2B | $1.8B | $1.6B | $1.4B |
| Gross profit | $2.2B | $2.1B | $1.8B | $1.6B | $1.4B |
| Operating income | $892.7M | $689.9M | $170.9M | $201.5M | $286.7M |
| Net income | $782.6M | $521.3M | $207.8M | $182.3M | $231.1M |
| Diluted EPS | $2.78 | $1.76 | $0.65 | $0.56 | $0.72 |
| Total assets | $2.8B | $2.9B | $2.9B | $3.1B | $2.6B |
| Total liabilities | $683.1M | $703.5M | $678.4M | $583.1M | $405.6M |
| Shareholders' equity | $2.2B | $2.2B | $2.3B | $2.5B | $2.2B |
| Cash and short-term investments | $1.1B | $1.1B | $995.3M | $1.3B | $1.5B |
| Total debt | $173.0M | $190.8M | $189.9M | $190.2M | $51.3M |
| Operating cash flow | $884.3M | $700.0M | $333.3M | $362.6M | $400.8M |
| Capital spending | $39.9M | $66.2M | $163.0M | $138.5M | $64.2M |
| Free cash flow | $844.3M | $633.8M | $170.4M | $224.2M | $336.6M |
In USD. Fiscal years as reported by the company; statements on this page go back to fiscal year 2020.
$2.32 billion, up 7.0% from $2.17 billion in fiscal year 2024.
Exelixis reported net income of $782.57 million for fiscal year 2025 (33.7% of revenue); operating income was $892.70 million.
At the end of fiscal year 2025: cash and short-term investments of $1.06 billion and total debt of $173.04 million.
$844.34 million in fiscal year 2025 (operating cash flow of $884.27 million minus capital spending of $39.93 million).