The largest holder of Nuvalent stock is Deerfield Management Co. LP (Private Equity), with 17.2 million shares (25.64% of the company), worth about $1.73 billion as of May 19, 2026. The 10 largest holders together own 76.3%.
In Q2 2026, 314 institutional holdings reports listed 81.7 million shares worth $9.35 billion, up 0.6% in shares from Q1 2026.
Insiders reported 50 transactions in the last two years: 25 sales worth $37.14 million and no purchases. The newest one on file is from October 30, 2025 (Miller Deborah Ann, Officer).
Major holders as of May 19, 2026; quarterly totals from institutional holdings reports (latest Q2 2026); insider transactions on file through October 30, 2025.

2026Q2
| Holder | Shares | % of company | Value |
|---|---|---|---|
| Deerfield Management Co. LP (Private Equity) | 17.2 million | 25.64% | $1.7B |
| Fidelity Management & Research Co. LLC | 9.3 million | 13.79% | $930.0M |
| Paradigm BioCapital Advisors LP | 5.3 million | 7.92% | $534.0M |
| BlackRock Advisors LLC | 4.4 million | 6.51% | $440.0M |
| JPMorgan Investment Management, Inc. | 3.1 million | 4.59% | $310.0M |
| RA Capital Management LP | 2.5 million | 3.77% | $254.0M |
| Vanguard Portfolio Management LLC | 2.5 million | 3.72% | $251.0M |
| Wellington Trust Co., NA | 2.5 million | 3.67% | $248.0M |
| Vanguard Capital Management LLC | 2.4 million | 3.61% | $244.0M |
| T. Rowe Price International Ltd. | 2.1 million | 3.06% | $206.0M |
As of May 19, 2026.
| Quarter | Reports | Shares | Value |
|---|---|---|---|
| Q2 2026 | 314 | 81.7 million | $9.4B |
| Q1 2026 | 274 | 81.2 million | $8.3B |
| Q4 2025 | 247 | 80.3 million | $8.1B |
| Q3 2025 | 206 | 74.1 million | $6.4B |
| Q2 2025 | 224 | 72.1 million | $5.5B |
| Q1 2025 | 220 | 72.2 million | $5.1B |
| Q4 2024 | 236 | 70.6 million | $5.5B |
| Q3 2024 | 218 | 70.2 million | $7.2B |
Shares and value held by institutions that file quarterly holdings reports (options not included).
| Insider | Date | Title | Transaction | Value |
|---|---|---|---|---|
| Miller Deborah Ann | Oct 30, 2025 | Officer | Conversion of Exercise of derivative security at price 6.89 per share. | $150,202 |
| Noci Darlene | Oct 30, 2025 | Officer | Conversion of Exercise of derivative security at price 27.85 per share. | $111,400 |
| Miller Deborah Ann | Oct 30, 2025 | Officer | Sale at price 96.65 - 104.78 per share. | $2.2M |
| Noci Darlene | Oct 30, 2025 | Officer | Sale at price 98.91 - 104.58 per share. | $411,661 |
| Shair Matthew | Oct 28, 2025 | Director | Sale at price 100.23 - 100.27 per share. | $6.0M |
| Miller Deborah Ann | Oct 20, 2025 | Officer | Conversion of Exercise of derivative security at price 6.89 per share. | $34,450 |
| Miller Deborah Ann | Oct 20, 2025 | Officer | Sale at price 94.91 per share. | $474,550 |
| Miller Deborah Ann | Oct 16, 2025 | Officer | Conversion of Exercise of derivative security at price 6.89 per share. | $192,920 |
| Porter James Richard | Oct 16, 2025 | Chief Executive Officer | Conversion of Exercise of derivative security at price 18.93 per share. | $511,110 |
| Miller Deborah Ann | Oct 16, 2025 | Officer | Sale at price 89.98 - 92.50 per share. | $2.5M |
| Porter James Richard | Oct 16, 2025 | Chief Executive Officer | Sale at price 90.01 - 92.63 per share. | $2.4M |
| Pelish Henry E | Oct 15, 2025 | Officer | Conversion of Exercise of derivative security at price 18.93 - 72.35 per share. | $498,260 |
Newest 12 of 50 insider transactions in the last two years.
Deerfield Management Co. LP (Private Equity), with 25.64% of the company (as of May 19, 2026). Next: Fidelity Management & Research Co. LLC (13.79%) and Paradigm BioCapital Advisors LP (7.92%).
314 institutional holdings reports listed Nuvalent shares in Q2 2026, 81.7 million shares in all worth $9.35 billion.
In the last two years insiders reported 25 sales and no purchases (50 transactions in all); the newest on file is from October 30, 2025.